The question behind most confusion here is: why so many injections? Antibodies from the mother protect a newborn early on — and the same antibodies interfere with vaccination. They fade at a different time in every individual, so a single early injection cannot reliably be the one that works. The series exists to catch the moment the animal can finally respond.
How we label our evidence
- Source-supportedStated directly in the cited institutional publication.
- Our editorial guidanceA conservative reading of the evidence applied to a caregiver decision. Not a validated clinical protocol.
- Evidence gapWe could not verify this in our approved sources, so we have not invented a number.
The core viral series
For DAP in puppies (distemper, adenovirus, parvovirus) and FVRCP in kittens (panleukopenia, herpesvirus-1, calicivirus), WSAVA 2024 recommends:
- Start at 6–8 weeks
- Repeat every 2–4 weeks
- Final dose of the initial series at 16 weeks or older — high-risk circumstances can justify continuing to 18–20 weeks
- Revaccinate at or shortly after 26 weeks, which catches animals that never responded earlier
A schedule of 8, 12, and 16 weeks is one illustration of a four-week interval. It is an example, not a prescription — shelter protocols, local disease pressure, and the specific vaccine product all change it.
Puppies
Core viral: AAHA specifies at least three combination doses between 6 and 16 weeks, 2–4 weeks apart, followed by a dose within one year of the initial series.
Leptospirosis: AAHA's 2024 update designates it core for all dogs — two doses 2–4 weeks apart starting at 12 weeks, then annual boosters. WSAVA treats it as core where the disease is endemic, relevant serogroups are known, and suitable vaccines exist. AAHA's is a regional recommendation, not a global rule.
Bordetella, influenza, Lyme: depend on exposure and location.
Rabies: timing and legal requirements vary by jurisdiction. Confirm with a veterinarian where you live — this is the one item on the page where the law, not just the medicine, decides.
Kittens
FVRCP: AAHA/AAFP 2020 — start no earlier than 6 weeks, repeat every 3–4 weeks until 16–20 weeks, and consider revaccination with the injectable combination at six months.
FeLV: core for cats under one year. Start as early as 8 weeks, two doses 3–4 weeks apart, with FeLV antigen testing beforehand. Revaccinate 12 months after the initial series, then reassess based on exposure. WSAVA specifies FeLV as core for young cats in regions where FeLV-associated disease is endemic.
Rabies: follows product labelling and local law.
Two things people get wrong: that indoor kittens need no vaccines, and that the six-month FVRCP visit also completes FeLV and rabies. These have separate indications and separate schedules.
Internal parasites
Merck's roundworm control example starts earlier than most people expect — at two weeks — and treats the nursing mother at the same time.
| Species | Schedule |
|---|---|
| Puppies | From 2 weeks, every 2 weeks until 3 months, then monthly until 6 months |
| Kittens | From 2 weeks, every 2 weeks through 12 weeks, then monthly until 6 months |
Watch for: poor growth, a pot belly, worms in vomit or faeces, diarrhoea, pale gums, or dark stools.
Flea and tick products
There is no single starting age that applies to every flea or tick medicine. Before using anything, check: species it is licensed for, active ingredients, formulation, minimum labelled age, minimum labelled weight, the animal's current weight, and what it has already had.
Call now for triage
After a vaccination
What the action labels mean
- Emergency now —
- contact an emergency veterinary service and arrange immediate assessment. Do not wait for the next scheduled feed or weigh-in.
- Call now for triage —
- telephone the veterinary service when you notice the sign. The veterinarian decides how quickly the animal needs to be seen.
- Contact today —
- get in touch when you notice the issue to agree on a time. This does not mean waiting until evening.
Emergency now
Call now for triage
Kittens
Injection-site lumps — the "3-2-1" rule. Have a lump investigated if it persists for 3 months, exceeds 2 cm, or is still enlarging 1 month after injection. Any one of the three qualifies.
This concerns examination and biopsy — it is not an emergency designation for every small lump after a shot.
Common misconceptions
- "One vaccination means fully protected." Maternal antibody interference is exactly why the series exists.
- "A negative stool test excludes parasites." See above.
- "Kittens must always start deworming at three weeks." Merck's example starts at two.
Sources
- WSAVA 2024 Vaccination Guidelines (PDF)
- AAHA Canine Vaccination Guidelines — Core and Noncore Recommendations
- AAHA Canine Vaccination Guidelines — Updated
- AAHA Postvaccination Adverse Events and Reactions
- AAHA / AAFP Core Vaccines for Pet Cats
- AAHA / AAFP Adverse Postvaccination Reactions
- Merck Veterinary Manual Roundworms in Small Animals
- Merck Veterinary Manual Gastrointestinal Parasites of Dogs
- Cornell Feline Health Center Fleas